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吸入用復方異丙托溴銨溶液

Compound Ipratropium Bromide Solution for Inhalation

適用于需要多種支氣管擴張劑聯合應用的病人,可使COPD患者肺功能得到明顯改善

中文名:  吸入用復方異丙托溴銨溶液

英文名 Compound Ipratropium Bromide Solution for Inhalation

商品名 可必特

主要成份 異丙托溴銨一水化物C20H30BrNO3·H2O;硫酸沙丁胺醇C26H44N2O10S

劑型規格:  霧化吸入溶液;2.5ml/

適應癥:  本品適用于需要多種支氣管擴張劑聯合應用的病人,用于治療氣道阻塞性疾病有關的可逆性支氣管痙攣。

開發階段:   

2011107日,德國勃林格殷格翰公司宣布,FDA批準其新一代噴霧吸入劑combivent respimat(可必特)上市,用于治療慢性阻塞性肺?。?/span>COPD),其活性成分為異丙托溴銨和沙丁胺醇組合物,該組合使患者肺功能得到更加明顯的改善。我國于2005年進口該產品,進口藥品注冊證號H20050296,商品名為可必特。

開發進度:  我公司已完成沙丁胺醇的原料藥合成工藝研究,異丙托溴銨原料即將通過關聯審評,制劑待進行工藝驗證。

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